Aptima® HIV-1 Quant Dx Assay

Aptima® HIV-1 Quant Dx Assay

HIV-1 Detection and Viral Load Monitoring With performance you can count on, the Aptima HIV-1 Quant Dx assay is a dual-claim assay that can be used to confirm HIV-1 infection and measure viral load for optimal patient management.1 It offers reliable quantitation of HIV-1 RNA across a broad linear range, giving your lab excellent precision and sensitivity for HIV-1 detection and viral load monitoring.
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Description

  • Confirm HIV Infection – Running on the Panther® system, Aptima HIV-1 Quant Dx accurately detects and monitors HIV-1 for reliable, repeatable results.
  • Monitor Viral Load – Industry-leading precision gives you confidence that any changes in viral load reflect clinical changes in the patient—not variations in the assay.

The Aptima HIV-1 Quant Dx assay design provides 3 levels of protection for confidence in assay performance despite drug selection pressures and growing genetic diversity:

 
  • Dual-target approach for built-in redundancy, with both targets chosen within highly conserved genomic regions of HIV-1 (LTR and pol) to ensure accurate quantitation
  • Sophisticated primer design to tolerate mutations
  • Redundant oligonucleotides for consistent performance

The Aptima HIV-1 Quant Dx Assay ensures detection and quantitation across major groups and subtypes (M, N, O)

  • Limit of Detection (LoD): The Aptima HIV-1 Quant Dx assay can detect HIV-1 RNA as low as 12 copies/mL (3rd WHO International Standard) using a 0.5 mL sample.
  • Lower Limit of Quantitation (LLoQ): The Aptima HIV-1 Quant Dx assay reports viral load as low 30 copies/mL.
 

Precise results reduce repeat testing

The Aptima HIV-1 Quant Dx assay delivers high precision in quantitation, with a narrow coefficient of variation across the linear range—including in low-viremia samples—for results you can trust.1

Features

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